Flights Chicago → Rome — September 21, 2026

One way · Economy · 1 adult · price per person

The cheapest itinerary observed for Monday, September 21, 2026 on the Chicago–Rome route: 2 stops itinerary (3 flights) via New York JFK (JFK) and Edinburgh (EDI), from Chicago O'Hare (ORD) to Rome Ciampino (CIA), first flight JetBlue B6906, departs 7:00 AM, arrives 8:00 PM the next day, total travel time 30h including layovers, flight time 12h 27m (layovers excluded), $386 per person. Fare as listed by Aviasales: carry-on bag not included (personal item only), checked bag not included, changes not allowed, non-refundable. Price found in an Aviasales search on September 10, 2026 and read by AirSource on September 10, 2026, 21:20 UTC: it is not guaranteed and is confirmed on Aviasales at booking time. The cheapest direct flight observed: Iberia IB8048, from Chicago O'Hare (ORD) to Rome Fiumicino (FCO), departs 4:55 PM, arrives 9:10 AM the next day, direct, 9h 15m, $625 per person. Fare as listed by Aviasales: carry-on bag included, checked bag not included, changes allowed for a fee, non-refundable.